
Take the situation in hand
Take matters into one's own hands / Take the bit in one's mouth

Prendere in mano la situazione 
Prendere in mano il pallino
Take matters into one's own hands / Take the bit in one's mouth

Prendere in mano la situazione 
Prendere in mano il pallino
Meanings
Fig.: to take control of a situation and manage it
Examples
If you want things to work out, you have to take matters into your own hands
Se vuoi che le cose vadano bene, ho paura che debba prendere in mano la situazione tu stesso
Just wait; you'll see the results when we take the situation in our hands
Aspetta solo quando riusciremo a prendere in mano il pallino e vedrai i risultati