Fig.: to harm or to hinder someone, interfering either in his work or in his life

I didn't mean to step on your toes when I asked Mary out. I didn't know you had a crush on her

Non volevo pestarti i piedi quando ho invitato Maria ad uscire con me; non sapevo che tu ne fossi invaghito

I'm sorry to step on your toes Miss Coleman, but Mr. Big changed my schedule and I'm changing yours

Mi dispiace pestarle i piedi sig.na Tersilli, ma il capo ha cambiato i miei programmi e io cambio i suoi

When working with other people you have to be careful not to twist anyone's tail

Quando si lavora con altre persone bisogna stare attenti a non pestare i piedi a nessuno