Fig.: to treat with extreme care either a person or a thing or a situation that, treated without precautions, could become sources of trouble

In some circles politics is something to be handled with kid gloves

In alcuni ambienti la politica è un argomento da prendersi con le molle

The new secretary is very touchy, so you'd better handle her with kid gloves

La nuova segretaria è molto suscettibile e bisogna prenderla con le pinze

You'd better handle that load with kid gloves: it's dynamite

Faresti meglio a prendere quel carico con le molle: è dinamite

Kidskin is a very soft skin from the smooth hide of a young goat. The expression probably originated as the opposite of “handle without gloves”, which means “to treat harshly”