Fig.: to get someone very angry; to drive someone crazy; to frustrate someone to the point of exasperation

It drives me up the wall when drivers park in the handicapped spot without even thinking twice, and then go shopping or have coffee with friends

Mi fanno uscire dai gangheri quegli automobilisti che, senza porsi problemi, occupano il parcheggio per handicap per andare a fare le spese o a prendere un caffè con gli amici

When my son didn't come home the whole night, and the next morning, cool as a cucumber, told me he was just having fun with his buddies, it really pissed me off

Quando mio figlio non è rientrato la notte e la mattina seguente mi ha detto pacifico e beato che era fuori a divertirsi con gli amici, mi ha veramente mandato in bestia

This image suggests a person who's literally climbing up a wall to escape a bother or a trouble