Be sick and tired of…

Be sick and tired of…
Be sick to death / Be sick and tired / Have had it / Be fed up with something / Have had it up to here

Averne le tasche piene 
Averne le scatole piene / Averne le palle piene (Volgare)

Averne le tasche piene
Be sick to death / Be sick and tired / Have had it / Be fed up with something / Have had it up to here

Averne le tasche piene 
Averne le scatole piene / Averne le palle piene (Volgare)

Averne le tasche piene
Meanings
Fig.: to be unable to tolerate someone or something any longer
Examples
What a hole! I'm sick to death of it and I'm sick to death of this stinking town!
Ne ho le palle piene di questo buco di casa e di questo schifo di città !
I'm sick and tired of getting all those unsolicited marketing calls at all hours of the day and night
Ne ho le tasche piene di tutte queste chiamate commerciali, non richieste, che arrivano a ogni ora del giorno