In a state of disorder; in a total mess; in a state of great confusion (also in a figurative way)

The dog was chasing a rabbit and the chase ended up with the flowerbeds at sixes and sevens

Il cane ha inseguito uno scoiattolo, inseguimento che ha trasformato le aiuole in un campo di battaglia

The subject of the final test hadn't been covered during the whole semester, that's why all the students were at sixes and sevens

L'argomento dell'esame finale non era stato trattato durante l'intero semestre, per cui tutti gli studenti erano in grande confusione

The parents are on vacation, their teenagers are home alone. Bottom line? The house is at sixes and sevens

I genitori sono in vacanza, i figli adolescenti sono a casa da soli, risultato? La casa è un campo di battaglia

During the Covid pandemia all the Emergency Rooms have been at sixes and sevens for months

Durante la pandemia da Covid, tutti i Pronto Soccorso si sono trovati in una situazione di estrema confusione per mesi

The original phrase – Set on six and seven – is found in Chaucer and it's said to be originated from a game of dice, where the players tried to throw a six and a seven, which is a very difficult combination by itself. Today's plural forms dates back to the 18th century